The pan-European Stoxx 600 was 0.12 percent lower with most sectors moving in negative territory.
• Shares faltered and the dollar skidded on Wednesday as investors fretted over the threat of new U.S. tariffs on Chinese imports, brushing aside data that showed the Asian economy got off to a solid start in 2018.
MSCI’s broadest index of Asia-Pacific shares outside Japan .MIAPJ0000PUS stumbled 0.7 percent, retreating from a 1-1/2 month high on Tuesday, with the technology sector the biggest drag.
• Japan’s Nikkei share average slid on Wednesday, ending a four-day winning streak, amid fears of rising U.S. protectionism after President Donald Trump fired his secretary of state and reportedly is eyeing hefty tariffs on Chinese imports.
The Nikkei ended 0.9 percent lower to 21,777.29, but stayed above its 25-day moving average of 21,672.57.
• China stocks retreated on Wednesday, weighed down by tech firms, as U.S. protectionism fears overshadowed strong China factory and investment data, while a regulatory crackdown on speculation dampened risk appetite further.
** At the close, the Shanghai Composite index was down percent at ,, while the blue-chips CSIindex ended percent lower at ,0.6 3291.38300 0.4 4073.34.