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The pan-European Stoxx 600 was 0.5 percent lower with almost every sector in the red.
In Asia, equities were mostly lower on the back of a Federal Reserve meeting. Stateside, the Fed decided to keep rates unchanged but said that it expects "further gradual increases," which pushed stocks slightly lower. Higher interest rates tend to dent stocks as investors believe companies will have less room for dividends.
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MSCI’s broadest index of Asia-Pacific shares outside Japan .MIAPJ0000PUS fell 1.3 percent and was headed for a loss of more than 1 percent for the week. On Thursday, the index hit its highest level since Oct. 8.
• Japan’s Nikkei ended the week on a sour note, tracking broader losses in global equities markets, and as worries about further Sino-U.S. trade tensions weighed on some China-focused shares.
The Nikkei share average closed 1.05 percent lower at 22,250.25, pulling back from a 2-1/2-week high reached during the previous session and erasing almost all gains it had made earlier in the week.
• Chinese stocks fell nearly 1.5 percent on Friday, posting their fifth straight session of declines, as the market was weighed down by a mix of weak data, worries over rising pressure on financial companies and concerns of a new board in Shanghai disrupting the already weak A-share market.
At the close, the Shanghai Composite index was down 1.4 percent at 2,598.87.
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